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The procedure works best for patients who have maintained stable weight for at least six months and have realistic expectations about achievable definition based on their underlying muscle development

An equal volume of Fer-1 (0.8 mg/kg/day) or 10% DMSO was painted on mouse ears 30 min before IMQ application

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Taken together, the above findings suggest that purine catabolism strongly associates with the TRP pathways leading to serotonin (5-hydroxytryptamine, 5-HT) and kynurenine metabolites