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DPP-4 Enzyme: The GLP-1 Breakdown Mechanism Research: Dong JX, et al
In many ways, Wegovy is simply a higher-dose version of Ozempic, as they both contain the same active ingredient
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Storage protocols exist because peptides are structurally fragile
It is a peptide similar to the hormone glucagon-like peptide-1 (GLP-1) but modified with a side chain
Etiology Genetics COL5A1 or COL5A2 mutation in 40-50% less common mutations identified below Associated conditions Connective tissue disorder characterized by Classification Berlin Classification (1988) - revised Types I - XI exist Villefranche Classification (1998) Presentation Symptoms double-jointedness easily damaged, bruised, & stretchy skin easy scarring & poor wound healing increased joint mobility, joint popping, early arthritis chronic musculoskeletal pain (50%) Physical exam a score of 5 or more on 9-point Beighton-Horan scale defines joint hypermobility
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