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First, three open-label, randomized, cross-over studies investigated nicotine pharmacokinetics and concluded that in smokers using the IQOS TM , a similar pharmacokinetic profile is obtained compared to smoking (IQOS TM : Cigarette ratios for maximal concentration, C max

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The FT says Reynolds is "interested" in the approach but wants more than the price currently on the table, which represents a 20 per cent premium to its closing price yesterday