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The authorized language says, The IQOS system heats tobacco but does not burn it, and that switching completely from cigarettes to IQOS significantly reduces exposure to harmful or potentially harmful chemicals

Some types of oral nicotine products are using synthetic nicotine that isnt derived from tobacco leaf, raising additional concerns about misleading consumers who may assume that nicotine that doesnt come from tobacco is somehow safer than tobacco-derived nicotine

Therefore, objective biomarkers for smoking, such as nicotine, cotinine, and exhaled carbon monoxide, have been investigated and used to validate the smoking status 9