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Common side effects may include: Mild injection-site reactions (redness, soreness, itching) Upset stomach or nausea Headache Mild anxiety or restlessness Rarely, allergic reactions If you experience difficulty breathing, severe dizziness, or hives, seek medical attention immediately

The recommendation for breaks is therefore precautionary and anecdotal rather than evidence-based

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High-dose oral supplementation may be another treatment option, because consuming 1,000 g (1 mg) per day of vitamin B 12 orally should result in the absorption of about 10 g/day (1% of dose) by passive diffusion