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As rightly noted, the systemic inflammation index (SII) is a composite measure derived from platelet, neutrophil, and lymphocyte counts, all of which are non-specific markers that can be elevated by a wide range of acute and chronic inflammatory conditions beyond smoking, such as infections, autoimmune diseases, malignancies, and other metabolic syndromes

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In the same way that frequent cannabis consumption will eventually decrease the strength of intoxication, regular pot users experience less fluctuation in blood pressure and heart rate and, in turn, lower levels of capillary dilation