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[ROS] For all postnatal days in the RP case and for PN15, PN17 and PN28 in the control case, changes in r , the parameter quantifying ROS creation due to photo-oxidation, drive the largest changes in the level of [ROS]

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Collectively, these results underscore the critical roles of P-SF3B1 and its interacting factors in pre-mRNA splicing and disease onset

doi: 10.1016/0167-4838(94)90086-8