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The image of Holmes, with his deerstalker hat and curved pipe, is instantly recognizable and has become a symbol of detective work and keen observation

Tobacco use also promotes pain sensitivity while simultaneously blunting the efficacy of many pain medications

Baseball has since cracked down on steroids, as well as amphetamines and other performance-enhancing drugs

Nearly one of every five deaths in the United States is smoking related (USDHHS, 2004)

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