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Results are generally subtle and progressive rather than dramatic, reflecting the gradual nature of cellular-level improvements in skin health

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In a phase 3, double-blind, randomized, controlled trial, 2,539 adults with a body-mass index (BMI) of 30 or greater, or 27 or greater with at least one weight-related complication, were given weekly subcutaneous injections of tirzepatide (5 mg, 10 mg, or 15 mg) or a placebo for 72 weeks

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Diabetes .1993;42(11):1678-1682