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Manny: Its the door outside

"We identified several genomic regions that were differentially altered in the lung tumor genomes of smokers and never smokers," Thu said in a statement

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In 1993, Waits memorably starred alongside Iggy Pop in the short film Coffee and Cigarettes III , a subtle, comic vignette in which the two men define themselves as a generation hooked on, you guessed it, caffeine and nicotine

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