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Male Myd88 / , Nlrp3 / , Casp1 / , Il1r / , Lyz Cre Nlrp3 flox or Itgax Cre Nlrp3 flox animals and control C57Bl/6 mice, aged 6 to 8 weeks, were bred and housed in a pathogen-free facility at the University of So Paulo

[12, 13] Use of rose hips as a preventative measure for joint pain, a characteristic of aging, is warranted