This could lead to situations where patients may also misattribute symptoms to their illicit GLP-1 medication, potentially missing the early diagnosis and treatment of unrelated illnesses, and as a result, poorer health outcomes for patients and increased costs to the NHS
GLP-1Rs are widely expressed in the whole body including the kidney [1, 10,11,12,13,14,15] and GLP-1 has diuretic and natriuretic effects in humans and animal models of hypertension, diabetes and obesity [10, 12, 13, 16]
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And although most prescriptions came from primary care physicians, those who were prescribed GLP-1s by endocrinologists or others with expertise in weight management were more likely to reach at least 12 weeks of continuous treatment
Note that compounded products are not FDA-approved finished medicines, which is a separate consideration from convenience