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reconstituted solutions should not be frozen unless explicitly stated in the SmPC

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Arifin N, Soo-Peng K, Long K, Chin-Ping T, Yusoff MSA, Oi-Ming L (2012) Modeling and optimization of lipozyme rm im-catalyzed esterification of medium- and long-chain triacyglycerols (MLCT) using response surface methodology

Early treatment is crucial to prevent serious complications

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