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J.s 2015 study, The role of mesoaccumbens dopamine in nicotine dependence reports that nicotine, one of the chemicals found in tobacco, is the primary cause of tobacco addiction

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Rather, its emphasis is on the thoughts, feelings, physical sensations, and behaviors the patient has learned to associate with the condition they are battling

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[155] Concerns have been raised that non-combustible nicotine products could lead adolescents and young adults to start smoking cigarettes later on