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Bibcode:2002PNAS...9916899M

There are many reasons an association can exist, but if the medication is not causing the adverse effect, then those associations are not a directly related safety concern

Technically yes, but it's not recommended

Why Muscle Loss Happens on GLP-1 Meds GLP-1s work by dramatically reducing your appetite, which can help with weight loss, but also makes it really easy to under-eat

The findings demonstrate that morroniside alleviates neuropathic pain by activating GLP-1R and modulating spinal microglial function, leading to IL-10-mediated -endorphin production and subsequent activation of -opioid receptors [74]