Among them, the best known ROS in human cells include superoxide anion (O 2 - ), which is the precursor of most other ROS, hydroxyl radical ( OH), peroxyl radical (ROO ), hydroperoxyl radical ( HO 2 ), and hydrogen peroxide (H 2 O 2 ), although the last one is not technically a free radical because it does not have unpaired electrons, but it represents a source of them [25] (Fig
These treatments can be delivered by bladder instillation or as oral medication
Targeting BTK with FDA-approved anticancer drugs, such as acalabrutinib and ibrutinib, which are metabolized by the CYP3A enzyme, common to both fungi and humans, can be combined with fungal morphogenesis inhibitors to enhance the apoptotic effect [183]
Let's go, Shemmy
10.1007/s12035-020-02115-w 95