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Since nicotine is a weak base (pKa=8.0), at a higher pH, a larger portion of nicotine is unprotonated (free-base) and nicotine is more volatile.62 Because of higher pH, a significant proportion of nicotine is present in the gas phase of inhaled aerosol

Lead researcher and psychiatrist Dr Marta Di Forti said: "If you decide to use high potency cannabis bear in mind there is this potential risk." Dr Adrian James from the Royal College of Psychiatrists said: "This is a good quality study and the results need to be taken seriously." Psychosis risk People experiencing psychosis lose touch with reality, and may hear voices, see things that are not actually there or have delusional, confused thoughts

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