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3.1 Polyphenols Polyphenols, which are abundant in various fruits, vegetables, and beverages, exhibit strong antioxidant properties, have garnered significant attention in the treatment of DN because their multifaceted roles in mitigating OS and inflammation associated with diabetes

Regarding hot flushes or temperature-related symptoms specifically, you should consult your doctor if : Hot flushes are severe, frequent, or significantly impacting quality of life You experience night sweats requiring clothing or bedding changes Temperature symptoms are accompanied by unexplained weight loss (beyond expected treatment effects), fatigue, or other systemic symptoms You have a personal or family history of thyroid disease, as thyroid dysfunction can cause temperature dysregulation Symptoms persist beyond the initial adjustment period (typically 48 weeks) Your clinician can perform appropriate investigations to exclude other causes such as thyroid disorders, menopausal transition, infections, or other medical conditions

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And actually, Satchin Panda, whos the expert about chronobiology and time-restricted feeding, he talks about 8 to 9 hours he thinks is the optimal feeding window for most individuals