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Be cautious of unregulated clinics offering unproven treatments, as these often lack long-term safety data and standardized manufacturing processes

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Suspected adverse reactions to any medicine, including unlicensed products, should be reported via the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk

The molecular-level understanding of OA pathogenesis has led to the identification of major catabolic enzymes, ADAMTS5 76 , MMP3 77 , and MMP13 78 , which mediate the degradation of cartilage matrix

This represents a change in how the digestive system processes food rather than a new food intolerance