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The decline in PI ABS is linked to decreased activity of the RC, which in turn diminishes the overall efficiency of these centers (Kalaji et al., 2014, 2017

Tobacco is a labour-intensive crop to grow, requiring over a year of work to gather the small seeds, grow them early in the year in cold frames, transplant to outdoor fields when the soil is warm, then weeding is necessary throughout the summer - "topping" plants to remove the flowers and force more of the plant's energy into the leaves