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48 h after transfection, cells were washed twice with pre-warmed PBS and fixed with 4% paraformaldehyde (PFA) for 1015 min

Regulation and targeting of Eg5 in blast crisis CML: overcoming Imatinib resistance

Relative data are presented relative to the WT, which was defined as 100%

Abstract The recent hype surrounding the antimelanogenic properties of glutathione has resulted in physicians frequently administering it as a wonder drug for skin lightening and treatment of hyperpigmentation, especially in ethnic populations with darker skin tones

However, after a large dose of APAP, the sulfonation reaction becomes saturated and the build-up of NAPQI depletes GSH in the liver, causing further accumulation of NAPQI