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Smoking has been shown to cause high rates of DNA methylation, and the team hypothesises that these regions of DNA may serve as long term markers of lung cancer risk and help identify the genes involved in lung cancer development

In contrast, the Cys349 to Tyr substitution alters the subcellular localization of ToMV replication proteins, such that replication proteins of L 11 tend to be membrane-bound, which causes a shortage of replication proteins in the soluble fraction

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