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In BRAF V600E-mutant CRC, tumor cells often exhibit an initial response to BRAF inhibitors, but frequently develop resistance through reactivation of the MAPK pathway, commonly via KRAS amplification or MEK mutations [76]

Hepcidin, a peptide hormone originated from the liver, regulates iron absorption and distribution by suppressing the activity of transferrin (45)

Since SLIM1 mRNA is not affected by S-starvation, the mechanisms of its action is not known, it is also not clear whether it actually binds to the SURE element

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Intern Info Matilda Bergsten Evaluation of herbivorous insect resistance amongst Card4, Card6, Card8 and DAO-1 mutant lines of Erysimum cheiranthoides The biosynthetic pathway of cardiac glycosides has not yet been fully deciphered