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doi:10.4103/1117-6806.137308

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Additionally, chemicals in cigarettes can damage cells and cause inflammation, impairing insulin response

Sampling of the mainstream smoke of cigarettes All the cigarettes and glass-fiber filter pads (Cambridge Filter Pad [CFP], Whatman, UK) were kept for 48 h under 22 o C and 60% RH according to the ISO 3308:2000 (routine analytical cigarette-smoking machine-definitions and standard conditions) and ISO 3402:1999 (atmosphere for conditioning and testing tobacco and tobacco products)

In a 1999, Centers for Disease Control and Prevention report, researchers estimated that more than 3,000 children and adolescents were becoming regular tobacco users daily