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The authors concluded that snus use did not appear to be a gateway to smoking among Swedish youth but instead was associated with low smoking prevalence among boys

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Controlling negative affective states (such as anxiety or insomnia) is the most frequent reason for abusing benzodiazepines, especially in women, according to a 2019 report by Votaw et al., titled The epidemiology of benzodiazepine misuse: A systematic review. More problematic use, such as co-ingestion with other substances, greater doses, non-oral administration (e.g., injection) and unlawful purchasing, is linked to recreational purposes (e.g., to get high).