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Description

However, recent studies have suggested that patients prescribed AOMs may regain weight in the months after stopping taking these medications

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DPP-4 cleaves GLP-1(7-36NH 2 ) and GLP-1(7-37) at the second N-terminal amino acid (Ala8) position, leading to metabolically metabolites GLP-1(9-36NH 2 ) and GLP-1(9-37) of much reduced potency (61)