ABC G5/G8 is a transmembrane heterodimer that transports plant sterols and excess cholesterol out of jejunal enterocytes (discussed in greater detail below)
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If this dysfunction is not promptly blocked, it will eventually lead to cell damage and death ( -synuclein accumulation and misfolding in the brain, leading to neurotoxicity ( Changes in mitochondrial dynamics include the highly dynamic process of fission-fusion
F.) 3779 (Royal Society of Chemistry, 2015)