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Besides weight gain, those who stop nicotine may immediately experience the following negative effects: Loss of appetite Food and nicotine cravings Tiredness or dizziness Headache Cough Constipation Nicotine relieves stress, so a lack of nicotine may lead to increased anxiety Restlessness Depression Irritability Lack of energy Reduced fertility The dangers of nicotine far outweigh any benefits of nicotine cessation

"Equally important is our finding that even after someone stops smoking, we still see the effects of smoking on their DNA," London said

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In terms of health risks, nicotine pouches are generally considered to be less harmful than traditional cigarettes