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That endotoxin result is notable because not all vendors submit samples for endotoxin screening, and contamination at this level can compromise injection-based research

Patients with significant bile acid diarrhea, severe pancreatic insufficiency, or active pancreatitis carry higher risk and may warrant closer monitoring or an alternative strategy entirely

Novo should be watching these outcomes closely

Imaging and biomarker assessments (such as for inflammation or cartilage changes) are typically missing, leaving the underlying mechanisms uncertain

doi: 10.1021/acs.biochem.9b00160 271 SenPLanYLiCYSidoliSDonahueGDouZet al