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"Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist for Obesity Treatment." New England Journal of Medicine , 2025 (ATTAIN-1 trial) Eli Lilly press release: ATTAIN-2 Phase 3 topline results

Perceived exertion was lower at 8 min ( p = 0.042), 9 min ( p = 0.035), 10 min ( p = 0.043), 11 min ( p = 0.028), 12 min ( p = 0.028), and 13 min ( p = 0.018) when compared to the placebo, suggesting that LC supplementation reduced the mental and physical strain during high-intensity exercise (Fig

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[DOI] [PubMed] [Google Scholar] 134.Nakagawa H., Hasumi K., Woo J.-T., Nagai K., Wachi M