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Reasons as to why this anti-inflammatory effect predominates in UC as opposed to CD remain uncertain, yet further differences in cytokine levels have been elucidated, with reduced IL-1 and IL-8 levels in smokers with UC and reduced IL-8 for smokers with CD [52]

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Mathis C, Poussin C, Weisensee D, Gebel S, Hengstermann A, Sewer A, Belcastro V, Xiang Y, Ansari S, Wagner S, Hoeng J, Peitsch MC (2013) Human bronchial epithelial cells exposed in vitro to cigarette smoke at the air-liquid interface resemble bronchial epithelium from human smokers