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REFERENCES: Bjrklund G, Doa MD, Maes M, Dadar M, Frye RE, Peana M, Chirumbolo S

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Calprotectin is an FDA-cleared inflammatory biomarker capable of helping differentiate IBS from inflammatory bowel disease, and a significantly elevated result should prompt referral and conventional workup including colonoscopy to rule out Crohn's or ulcerative colitis not a permeability-repair protocol

After therapy, Ki67 expression decreased, while levels of claudin-1 and claudin-4 increased