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Clinical studies demonstrate strong correlations between OS markers and vascular complications including diabetic kidney disease (Forbes and Thorburn, 2018

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No reproductive toxicity or teratogenicity has been documented in the Russian preclinical dossier, but Western long-term human safety data beyond 30 days do not exist

Consistently, there are no significant effects of AMSCs administration on restoring impaired mitochondrial function in APAP-challenged Ddit4 Hep mice, as reflected by no improvement in mtDNA content or mitochondrial OCR (Fig