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doi:10.1089/scd.2014.0180

Therefore, this indicates that Epitalon has a strong inhibitory effect on colon mucosal carcinogenesis when the treatment is continued

Because these are two different rate-limiting steps, addressing only one leaves the other in place

The selective mechanism that avoids systemic hormonal disruption suggests potential for extended use compared to interventions that create metabolic or endocrine imbalances requiring periodic breaks

doi: 10.3390/nu9010053