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Additional studies, including longer-term toxicology, will also be conducted during the grant term to support future Phase 2a efficacy studies

297: 83-95 [DOI] [PMC free article] [PubMed] [Google Scholar] 47).Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, Abela GS, Franchi L, Nuez G, Schnurr M, Espevik T, Lien E, Fitzgerald KA, Rock KL, Moore KJ, Wright SD, Hornung V, Latz E: NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

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