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or (2) for devices for which pass-through status will begin on or after January 1, 2020, as an alternative to the substantial clinical improvement criterion, the device is part of the FDA's Breakthrough Devices Program and has received FDA marketing authorization for the indication covered by the Breakthrough Device designation

Effect of sitagliptin on post-prandial glucagon and GLP-1 levels in patients with type 1 diabetes: investigator-initiated, double-blind, randomized, placebo-controlled trial

In healthy digestion, strong muscular contractions push food through the digestive tract

Serious psychiatric side effects, like mood changes (depression, mania), psychosis, hallucinations, paranoia, delusions, thoughts of suicide, and other serious events have been reported in patients using bupropion for smoking cessation

Characterised by Francis and colleagues in the Journal of Molecular Endocrinology in 1992