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Concerning symptoms accompanying hunger : Seek prompt medical attention if persistent hunger occurs alongside symptoms such as excessive thirst, frequent urination, unexplained weight loss despite increased appetite, or signs of hypoglycemia (shakiness, sweating, confusion)

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A previous study highlighted that they increase nitric oxide production, reduce oxidative stress and promote microvascular recruitment, including in the retina and optic nerve, through direct actions on vascular endothelium

The Lundgren protocol used moderate-to-vigorous aerobic-dominant exercise (cycling, running, circuit training) and still produced lean preservation