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Even when dietary sources of carnitine are insufficient, the human body produces enough from methionine and lysine to maintain functional carnitine stores

Cells were cultured in Dulbeccos modified Eagles medium (DMEM) (Gibco, NY, USA) supplemented with 10 % foetal bovine serum (FBS) (Gibco, NY, USA) and were maintained in a humidified incubator at 37 C and 5 % CO 2

These peptides serve as signal molecules to trigger cascade reactions or as substrates involved in biological activities ( Integrins, the cell adhesion molecules, are expressed in the cell surface and extracellular matrix (ECM)

Additional studies have revealed that hyperphosphorylated tau protein can directly enhance the transcription of ACSL4, thereby intensifying the activity of the PUFAphosphatidylethanolamine (PUFAPE) pathway and accelerating lipid peroxidation

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