Although a modest benefit of GLP-1RA in preventing HF hospitalizations has emerged, this finding deserves to be confirmed in mechanistic studies
Hypothalamus is known as the control panel of large numbers of hormones, hypothalamic releasing and inhibiting hormones such as corticotropin-releasing hormone (CRH), thyrotropin-releasing hormone (TRH), growth hormone-releasing hormone, somatostatin (SS), also called growth hormone-inhibiting substance, gonadotropin-releasing hormone (GnRH), dopamine, etc
This integrative approach could pave the way for innovative therapies that address the multifactorial nature of DN
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in vitro or in vivo models (Zhao et al., 2010