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Semaglutide is another GLP-1 RA and is the active ingredient in Wegovy weight loss pens

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At baseline, eGFR was 90 mL/min/1.73 m2 in 53%, 60 to 90 mL/min/1.73 m2 in 39%, 45 to 60 mL/min/1.73 m2 in 7%, and 30 to 45 mL/min/1.73 m2 in 1% of patients

The condition, called ischemic optic neuropathy (ION), occurs when blood flow to the optic nerve is reduced or blocked

These insights alone do not predict exact medication response but can support a more informed conversation with your provider about whether metformin-tirzepatide combination aligns with your metabolic biology