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The certificate, released on Monday, local time, lists the pulmonary embolism, which occurs when a blood clot blocks an artery in the lungs, as the immediate cause of the actor's death at age 71

After a few days, dyspnea becomes ARDS (Acute Respiratory Distress Syndrome), or fluid in the lungs

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Smokers have increased airway expression of ACE-2, the entry receptor for the virus, and could have an increased risk of severe COVID-19 by activating a cytokine storm 3-5