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The pyrenyl and anthracenyl complexes are appropriate DNA binders with intercalative properties, surpassing the activity of Pt II -12 (Figure 20)

In response to extracellular stimuli, MEK5 directly phosphorylates the threonine and tyrosine residues within a TEY motif in the activation loop of the N-terminal kinase domain, thereby inducing ERK5 activation

Nonoyama et al

Biologically, these three peptides promote tissue repair through distinct but complementary mechanisms

Finally, the slices were subjected to secondary antibody (1:50, A0208, Beyotime, Shanghai, China) incubation, DAB (D8001, Sigma-Aldrich Chemical Company, St Louis, MO, USA) staining, and hematoxylin (H9627, Sigma-Aldrich) nuclear counterstaining