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We recently showed that exposure of primary human bronchial epithelial cells (HBEC) to e-cig aerosols of 100% VG, in the absence of any nicotine or flavors, reduced the function of cystic fibrosis transmembrane conductance regulator (CFTR), an anion channel important for mucus hydration 19
132,137,139,143 Five studies investigated baseline comorbid depression and anxiety with subsequent tobacco dependence, of which three (60%) found evidence to support this association, 144146 while two (40%) found no evidence of an association
I know it because Ive done it thousands of times
Although the drugs arent addictive, they do have potential side effects, which could include changes in behavior, depressed mood, hostility, aggression, and suicidal thoughts or actions, according to the FDA