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In iPSC-based models, the transcription factors, such as SOX18, TLAL1, SOX7, and ETS1, act in synergy to enhance BBB function and integrity (Roudnicky et al., 2020)

As an important group of antioxidative enzymes, the normal levels of GPxs help to control the level of reactive species

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As monotherapy, in a phase 2 study, cagrilintide led to significant reductions in body weight and was well-tolerated in participants with overweight or obesity [10]