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One pivotal trial followed patients taking 600mg of racemic ALA daily for four years and found no significant safety concerns.7 We explore the differences between racemic ALA and R-ALA later in the guide, but its worth noting here: racemic ALA has the strongest long-term safety data in humans

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It must be noted that other antibacterial agents, in addition to amoxicillin, were used in these studies such as cefprozil, clarithromycin, metronidazole, ciprofloxacin that are not directly comparable to amoxicillin-clavulanic acid in terms of the impact on gut microbiota

General Anesthetics on Immune System Cytokines: A Narrative Review Article