Animal model studies have suggested that GLP-1RAs may cause pancreatitis and exocrine dysplasia, but in the large RCTs and a meta-analysis, GLP-1RAs did not increase the risk of pancreatitis or pancreatic cancer [82,83]
Retraining hunger and fullness cues is a cornerstone of treatment for many eating disorders
Managing and Treating Skin Reactions Most local skin reactions to Mounjaro can be effectively managed with simple self-care measures and proper injection technique
If you developed NAION or experienced sudden vision loss after taking Wegovy or another semaglutide medication, you may have grounds to file a lawsuit against the drugs manufacturer for failing to adequately warn you about this risk
Summary Clinical Presentation Symmetrical, velvety, hyperpigmented plaques on the hair-bearing surface of the vulva and groins Histologic Features Papillomatosis and hyperkeratosis but with very mild acanthosis No melanocytic proliferation and no dermal inflammation Differential Diagnosis Lichenified eczema Physiologic hyperpigmentation Takeaway Essentials Clinical Relevant Pearls Symmetrical hyperpigmentation with brown, poorly demarcated, thickened velvet-textured plaques with verrucous excrescences Pathology Interpretation Pearls Papillomatous hyperplasia without acanthosis Hypopigmentation Post-inflammatory Hypopigmentation Clinical Features Cutaneous infections (e.g., syphilis, leprosy, herpes) and many inflammatory conditions (atopic dermatitis, pityriasis lichenoides chronica (PLC), psoriasis, lichen striatus, and lichen sclerosus) can induce post-inflammatory hypopigmentation [25] (Figs
