Tobacco products are regulated in Canada, and availability may vary by province, retailer, age-verification rules, and local regulations
E-cigarettes may contain several potentially harmful substances, including: nicotine and other tobacco products flavoring such as diacetyl, which research has linked toa serious lung disease chemicals that may cause cancer heavy metals volatile organic compounds ultrafine particles that a person may inhale deep into the lungs In 2018, approximately However, the organization warns that people who do not smoke should not start vaping
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Nicotine is a naturally occurring chemical that is produced by the tobacco plant as an insecticide

Food and Drug Administration (2024) Drinking levels and patterns defined, National Institute on Alcohol Abuse and Alcoholism (2024) Alcohol related liver disease, University of Michigan Health (2023) Fluconazole, LiverTox (2017) Understanding alcohol use disorder, National Institute on Alcohol Abuse and Alcoholism (2024) Pharmacokinetics and tissue penetration of fluconazole in humans, Reviews of Infectious Diseases (1990) Antifungal drugs and drug-induced liver injury: A real-world study leveraging the FDA adverse event reporting system database, Frontiers in Pharmacology (2022) Impact of alcohol on inflammation, immunity, infections, and extracellular vesicles in pathogenesis, Cureus (2024) Blood cell responses following heavy alcohol consumption coincide with changes in acute phase reactants of inflammation, indices of hemolysis and immune responses to ethanol metabolites, International Journal of Molecular Sciences (2022) Medically accurate: SingleCares Medical Review Board analyzes all of our content to confirm its in line with current medical advice
