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1,2 Serum vitamin B 12 levels may be artificially elevated in patients with alcoholism, liver disease, or cancer because of decreased hepatic clearance of transport proteins and resultant higher circulating levels of vitamin B 12

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A bone that has high bone density will be stronger and less likely to fracture

Adverse events outcomes (n = 21,229) were reported including 1,039 deaths (4.9% of all reports), 1,613 life-threatening events (7.6%), and 7,426 hospitalizations (35%)