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Direct antimicrobial effects (against both bacteria & viruses) with higher dosages

this proportion is more consequential in adults over 65 who have lower baseline muscle mass and anabolic resistance Associated risks in older adults: Accelerated sarcopenia, bone density decline, malnutrition from reduced food intake, and dehydration from reduced fluid intake Trial representation: GLP-1 trial populations included older adults but in numbers insufficient to characterize age-specific body composition changes or functional outcomes What it does not prove: That GLP-1 drugs cause clinically significant harm in all older adults

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