doi: 10.4103/0974-7753.111215
The authors concluded that intra-articular BPC 157 injection could be a promising treatment option for patients with various types of knee pain, including osteoarthritis, patellar tendonitis, and meniscal tears
Forouhar F, Lee IN, Vujcic J, Vujcic S, Shen JW, Vorobiev SM, et al
marketed as Mounjaro for T2DM and Zepbound for obesity), is a 39-amino acid peptide acylated with a C20:0 fatty diacid moiety to lysine residue at position 20 with a molecular weight of 4.8 kDa [ Figure 2 , Table 1 ]
We employed a method that has been reported to measure conformational changes in cell surface receptors, namely trFRET, to investigate the impact of ITP on the conformation of the N-terminal SNAP-tagged version of the IR (Fig